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Image Search Results
Journal: International Journal of Molecular Sciences
Article Title: The Attenuated Secretion of Hyaluronan by UVA-Exposed Human Fibroblasts Is Associated with Up- and Downregulation of HYBID and HAS2 Expression via Activated and Inactivated Signaling of the p38/ATF2 and JAK2/STAT3 Cascades
doi: 10.3390/ijms22042057
Figure Lengend Snippet: Effects of UVA on phosphorylation and protein levels of p38/ERK/JNK. HDFs were exposed to UVA at the indicated doses in culture and cell lysates prepared at the indicated times post-irradiation were subjected to western blotting as described in the Materials and Methods section. Representative immunoblots from three independent experiments are shown.
Article Snippet: The p38 inhibitor (SB239063) and the
Techniques: Phospho-proteomics, Irradiation, Western Blot
Journal: International Journal of Molecular Sciences
Article Title: The Attenuated Secretion of Hyaluronan by UVA-Exposed Human Fibroblasts Is Associated with Up- and Downregulation of HYBID and HAS2 Expression via Activated and Inactivated Signaling of the p38/ATF2 and JAK2/STAT3 Cascades
doi: 10.3390/ijms22042057
Figure Lengend Snippet: Effects of signaling inhibitors on mRNA expression levels of HAS2 and HYBID in HDFs. Effects of inhibitors of p38, JNK, NF-kB, and STAT3 on UVA- or sham-stimulated mRNA expression of HAS2 in HDFs. Signaling inhibitors were added at the indicated concentrations immediately after UVA irradiation at 10 J/cm 2 or sham irradiation. Cell lysates prepared at the indicated times post-irradiation were subjected to RT-qPCR analysis. ( a ) p38 inhibitor, 12 h, n = 4, ( b ) JNK inhibitor, 12 h, n = 4, ( c ) NF-kB inhibitor, 3 h, n = 4, ( d ) STAT3 inhibitor, 3 h, n = 4, *: p < 0.05, **: p < 0.01.
Article Snippet: The p38 inhibitor (SB239063) and the
Techniques: Expressing, Irradiation, Quantitative RT-PCR